A synergistic formula which combines the plants traditionally used in South America for nausea, vomiting, stomachaches, and queasy or nervous stomachs.* For more information on the individual ingredients in Stomach-Ez, follow the links provided below to the plant database files in the Tropical Plant Database.

Ingredients: A herbal blend of ayapana, condurango, canchalgua, matico, piri-piri, and culen extracted in distilled water and vegetable glycerine. To prepare this natural remedy yourself: use one part of each of the plants in the list. To make a small amount... "1 part" could be one tablespoon (you'd have 6 tablespoons of the blended herbal formula). For larger amounts, use "1 part" as one ounce or one cup or one pound. Combine all the herbs together well. Follow the instructions provided for a strong decoction on the Methods of Preparing Herbal Remedies page. After the decoction is finished and strained, add 1 part glycerine (or honey) to two parts decoction. Mix well and store in the refrigerator. Alternatively, the powdered herbal mixture can also be stuffed into capsules or brewed into tea, stirred into juice or other liquid, or taken however you'd like.

Suggested Use: Take 1-2 ml as needed.
Contraindications: Not to be used during pregnancy or while breast-feeding.
Drug Interactions: None reported.

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Third-Party Published Research*

This rainforest formula has not been the subject of any clinical research. A partial listing of the published research on each herbal ingredient in the formula is shown below. Please refer to the plant database files by clicking on the plant names below to see all available documentation and research.

Ayapana (Ayapana triplinervis)
In Brazilian herbal medicine ayapana is traditionally used for queasy stomachs, indigestion, diarrhea, fever, headaches, insomnia, nausea and vomiting, and stomach ulcers.*
Kokate, C. K., et al. "Pharmacological studies on the essential oil of Eupatorium triplinerve. I. Effects on the central nervous system and antimicrobial activity." Flavour. 1971; 2 (3): 177-180.
Jelager, L., et al. "Antibacterial and antifungal activity of medicinal plants of Mauritius." Pharmaceutical Biol. 1998; 36:153-161.
Gupta, M., et al. "Antimicrobial activity of Eupatorium ayapana." Fitoterapia. 2002; 73 (2):168-170.
Verpoorter, R., et al. "Medicinal plants of Surinam. IV. Antimicrobial activity of some medicinal plants." J. Ethnopharmacol. 1987; 21: 315-318.

Condurango (Marsdenia cundurango)
In Brazilian herbal medicine condurango is used for appetite loss, dyspepsia, gastralgia, gastritis, neuralgia, stomachaches, stomach cancer, stomach ulcers, and rheumatism.*
Yamasaki, K., et al. "Studies on the effect of crude drugs on enzyme activites (IV) Influence of stomachic crude drugs on digestive enzymes." Shoyakugaku Zasshi. 1986; 40(3): 289-294.
Ortega, T., et al. "Anti-inflammatory activity of ethanolic extracts of plants used in traditional medicine in Ecuador." Phytother. Res. 1996: S121-S122.
Grange, J. M., et al. "Detection of antituberculous activity in plant extracts." J. Appl. Bacteriol. 1990; 68(6): 587-591.

Canchalagua (Schkuhria pinnata)
In Peruvian herbal medicine systems canchalagua is often relied on to ease nausea and stomachaches, and as a general digestive aid.*
Perez, C., et al. "Inhibition of Pseudomonas aeruginosa by Argentinean medicinal plants." Fitoterapia. 1994; 65(2): 169-172.
Anesini, C., et al. "Screening of plants used in Argentine folk medicine for antimicrobial activity." J. Ethnopharmacol. 1993; 39(2): 119-128.
Weimann, C., et al. "Spasmolytic effects of Baccharis conferta and some of its constituents." J. Pharm. Pharmacol. 2002; 54(1): 99-104.
Nam, N. H. "Naturally occurring NF-Kappa-B inhibitors." Mini. Rev. Med. Chem. 2006; 6(8): 945-51.

Matico (Piper aduncum)
The Shipibo-Conibo Indians of the Peruvian Amazon traditionally use matico for inflammation, diarrhea, gastritis, vomiting, fever, menstrual colic, internal infections and as a postpartum tonic.*
Kloucek, P., et al. "Antibacterial screening of some Peruvian medicinal plants used in Calleria district." J. Ethnopharmacol. 2005 Jun; 99(2): 309-12.
Lentz, D. L., et al. "Antimicrobial properties of Honduran medicinal plants." J. Ethnopharmacol. 1998; 63(3): 253-263
Orjala, J., et al. "Cytotoxic and antibacterial dihydrochalcones from Piper aduncum." J. Nat. Prod. 1994; 57(1):18-26
Orjala, J., et al. "Aduncamide, a cytotoxic and antibacterial beta-phenylethylamine-derived amide from Piper aduncum." Nat. Prod. Lett. 1993; 2(3): 231-236.

Piri-Piri (Cyperus articulatus)
Piri-piri has a long history of use in herbal medicine systems in South America as a common remedy for nausea, vomiting, stomachaches, and intestinal gas throughout the continent.*
Bum, E. N., et al. "Anticonvulsant properties of the methanolic extract of Cyperus articulatus (Cyperaceae)." J. Ethnopharmacol. 2001 Jul; 76(2): 145-50.
Rakotonirina, V. S., et al. "Sedative properties of the decoction of the rhizome of Cyperus articulatus." Fitoterapia. 2001; 72(1): 22-9.
Bum, E. N., et al. "Effect of the decoction of rhizomes of Cyperus articulatus on bicuculline-, n-methyl-d-aspartate- and strychnine-induced behavioural excitation and convulsions in mice." J. Cameroon Acad. Sci. 2002; 2: 91-95.
Bum, E. N., et al. "Organic and water extracts of Cyperus articulatus (Cyperaceae)inhibited chemically and electrically-induced convulsions in mice." J. Cameroon Acad. Sci. 2002; 2: 96-106.

Culen (Psoralea glandulosa)
In South American herbal medicine systems culen is traditionally used for enteritis, digestive disorders, and stomachaches among other things.*
Backhouse, C., et al. "Active constituents isolated from Psoralea glandulosa L. with antiinflammatory and antipyretic activities." J. Ethnopharmacol. 2001; 78(1): 27-31.
Ferrandiz, M., et al. "Effect of bakuchiol on leukocyte functions and some inflammatory responses in mice." J. Pharm. Pharmacol. 1996; 48(9): 975-980.
Backhouse, N., et al. "Antiinflammatory and antipyretic activities of Cuscuta chilensis, Cestrum parqui and Psoralea glandulosa." Int. J. Pharmacog. 1996; 34(1): 53-57.
Erazo, S., et al. "Antimicrobial activity of Psoralea glandulosa L." Int. J. Pharmacog. 1997; 35(5): 385-387.
Kaul, R. "Kinetics of the antistaphylococcal activity of bakuchiol in vitro." Arzneim-Forsch. 1976; (26): 486-513.

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