Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Brunfelsia uniflorus (POHL) D. DON. (Solanaceae) -- Manaca

Chemicals

BRUNFELSENE Plant: DUKE1992A

No activity reported.

ESCULETIN Bark: DUKE1992A

5-Lipoxygenase-Inhibitor IC50=0.1-5 uM; Analgesic PMP24:107 ; Antiarrhythmic DUKE1992B ; Antiasthmatic? PMP24:107 ; Antibacterial JBH ; Anticapillary-Fragility WIC ; Antidysenteric HG24:37 ; Antiinflammatory; Antimutagenic EMP6:235 ; Antipyretic FT67:483 ; Antiseptic JE39:205 ; Cancer-Preventive 525 ; Cardiodepressant DUKE1992B ; Choleretic FT5:1986 ; Cosmetic FT67:483 ; Cytotoxic MAB ; Dermatitigenic WIC ; Fungicide; Hypertensive CCO ; Lipoxygenase-Inhibitor; Musculotropic WIC ; Myorelaxant WOI ; Pesticide DUKE1992B ; Sunscreen IC100=50 mg/l FT64:134 IC98=20 mg/l FT64:134 ; UV-Screen WIC ; Xanthine-Oxidase-Inhibitor IC52=10 uM AJC24:11

HOPEANINE Bark 4 ppm; DUKE1992A

No activity reported.

MANACEINE Bark 800 ppm; DUKE1992A

No activity reported.

MANACINE Bark 800 ppm; DUKE1992A

No activity reported.

MANDRAGORINE Plant: DUKE1992A

Anticholinergic DUKE1992B ; Bronchodilator DUKE1992B ; CNS-Stimulant DUKE1992B ; Mydriatic DUKE1992B

SCOPOLETIN Plant: DUKE1992A

Aldose-Reductase-Inhibitor IC50=6.2 ug/ml cow CPB43:1385 ; Allelochemic IC89=2 mM 438 ; Analgesic PM56(6):595 ; Antiarrhythmic IWU ; Antiasthmatic DUKE1992B ; Antibacterial JBH ; Antibronchoconstrictor IWU ; Anticholinergic KCH ; Antiedemic DUKE1992B ; Antifeedant 382 ; Antihepatotoxic BIS ; Antiinflammatory ED 1-10 ug/ear PM56(6):504 ; Antileukotrienogenic PM56(6):595 ; Antimutagenic MAB ; Antioxidant PH2 ; Antiprostaglandin RWG27 ; Antiseptic FT1990:503 ; Antispasmodic; Antitumor 2.9 ug/ml DUKE1992B ; Bronchorelaxant KCH ; Cancer-Preventive 525 ; Cholagogue WIC ; Choleretic KCH ; CNS-Depressant KCH ; CNS-Stimulant WBB ; Cytotoxic MAB ; Fungicide 2 mM BIOSIS'96 ; Hepatoprotective WIC ; Herbicide JBH ; Hypoglycemic EMP6:165 ; Hypotensive FT#3:141.1986 ; Musculotropic WIC ; Myorelaxant WOI ; Pesticide DUKE1992B ; Phytoalexin PC29(6):1789 ; Phytohormonal JBH ; Uterosedative 411

STARCH Bark 13,000 ppm; DUKE1992A

Absorbent M29 ; Antidote (Iodine) JBH ; Antinesidioblastosic M29 ; Emollient M29 ; Poultice M29

References

382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.

438: Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.

525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

AJC24:11: Jim Duke's personal files

BIOSIS'96: Jim Duke's personal files

BIS: Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Note: English translation of Wichtl, 1984,1989).

CCO: Chemical Constituents of Oriental Herbs (3 diff. books)

CPB43:1385: Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387

DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EMP6:165: Economic & Medicinal Plant Research, 6: 165

EMP6:235: Economic & Medicinal Plant Research, 6: 235.

FT#3:141.1986: Jim Duke's personal files

FT1990:503: Jim Duke's personal files

FT5:1986: Fitoterapia No.5-1986.

FT64:134: Lazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.

FT67:483: Jim Duke's personal files

HG24:37: HerbalGram No. 24, page 37.

IWU: Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JE39:205: Jim Duke's personal files

KCH: Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

M29: Martindale's 29th

MAB: Mills, Simon and Bone, Kerry. 2,000. Phytotherapy. Churchill Livinston, Edinburgh.

PC29(6):1789: Jim Duke's personal files

PH2: Jim Duke's personal files

PM56(6):504: Jim Duke's personal files

PM56(6):595: Jim Duke's personal files

PMP24:107: Jim Duke's personal files

RWG27: Jim Duke's personal files

WBB: Watt, J.M. and Breyer-Brandwijk, M.G. 1962. The Medicinal and Poisonous Plants of Southern and Eastern Africa. E. & S. Livingstone, Ltd. Edinburg & London. 1457 pp.

WIC: Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.

WOI: ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.

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